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When you say Biological course, are you referring to Biological sciences? If yes, then all Biological Siences courses require that you have alteast C (plain) in Mathematics. You might want to consider Social Sciences, Media Studies, Fine Arts, etc.
With that performance in Mathematics, options are very limited. You might want to consider religious studies courses in colleges or Artisan courses offered in TVET institutions.
First of all, P1 course is no longer offered in Tracher Training colleges. Diploma in primary education is the new minimum qualification for primary teaching. The entry grades are: A minimum of C plain in KCSE. A minimum of C plain in Maths, English, Kiswahili A minimum of C plain in either Physics, Chemistry or Biology A minimum of C plain in one humanity subjects e.g History, CRE, IRE.
Yes, you can do a diploma with KCSE grade E in Maths depending on the course you want to do. If you are doing a diploma course with Maths as one of the required subjects then you cannot do the course with grade E. However, there are many available diploma courses that do not require Maths as one of the subjects to consider.
You can apply for any diploma medicine related courses offered in KMTC. For instance, Clinical Medicine, Medical Laboratory sciences, Radiography and Imaging, Pharmacy, etc. However, you must have C (plain) in Physics since they require C (plain) in either Maths or Physics. Here is a complete list of all the courses offered in KMTC and their requirements: https://kmtc.ac.ke/wp-content/uploads/2020/02/KMTC-Programmes-Courses-Feb-2020.pdf Alternatively, consider doing any degree course that is not related to medicine and which Maths is not a requirement.